Invention Grant
- Patent Title: Method of producing microparticles
- Patent Title (中): 微粒的制造方法
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Application No.: US10597328Application Date: 2005-01-19
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Publication No.: US08343545B2Publication Date: 2013-01-01
- Inventor: Abdul Waseh Basit , Richard Andrew Kendall , Sudax Shina Murdan
- Applicant: Abdul Waseh Basit , Richard Andrew Kendall , Sudax Shina Murdan
- Applicant Address: GB London
- Assignee: University College London
- Current Assignee: University College London
- Current Assignee Address: GB London
- Agency: Dewitt Rose & Stevens, SC
- Agent Charles S. Sara, Esq.; Daniel A. Blasiole
- Priority: GB0401291.0 20040121; GB0418141.8 20040813
- International Application: PCT/GB2005/000174 WO 20050119
- International Announcement: WO2005/070391 WO 20050804
- Main IPC: A61K9/14
- IPC: A61K9/14 ; A61K9/16 ; B01F3/00 ; B01F3/08
Abstract:
A method of producing microparticles having a median diameter up to 100 μm and the microparticles so produced are described. The method includes the steps of providing a solvent having a bioactive dispersed or dissolved therein and a vehicle dissolved therein, carrying out an emulsification in a non-solvent phase to produce an emulsion containing the bioactive and the vehicle in a solvent phase, and evaporating the solvent to leave the microparticles, wherein a mixture of at least two surfactants is employed to stabilize the emulsion and wherein the mixture has a hydrophilic-lipophilic balance (HLB) of up to 8.
Public/Granted literature
- US20080241251A1 Method of Producing Microparticles Public/Granted day:2008-10-02
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