A polymer electrolyte fuel cell is provided with a fuel cell stack assembled by sandwiching a plurality of stacked single cell modules with a plurality of fastening members through a pair of end plates. The fuel cell includes a first elastic member arranged between the fastening member and the end plate and a plurality of second elastic members arranged between the end plate and the end of the fuel cell stack. Each of the second elastic members is arranged on the surface of the end plate corresponding to the electrode portion of a membrane electrode assembly in each of the single cell module, and each of the first elastic members is arranged on the surface of the end plate corresponding to a seal member arrangement region in which the seal member is arranged between the periphery of the membrane electrode assembly and a pair of separator plates in each single cell module.