Invention Grant
- Patent Title: Microrna as biomarker in cancer
- Patent Title (中): Microrna作为癌症中的生物标志物
-
Application No.: US12513007Application Date: 2007-10-30
-
Publication No.: US08343719B2Publication Date: 2013-01-01
- Inventor: Jingfang Ju , Yaguang Xi , Nakajima Go
- Applicant: Jingfang Ju , Yaguang Xi , Nakajima Go
- Applicant Address: US NY Albany
- Assignee: Research Foundation of State University of New York
- Current Assignee: Research Foundation of State University of New York
- Current Assignee Address: US NY Albany
- Agency: The Webb Law Firm
- International Application: PCT/US2007/083005 WO 20071030
- International Announcement: WO2008/055158 WO 20080508
- Main IPC: C12Q1/68
- IPC: C12Q1/68

Abstract:
The present invention relates to the discovery of certain microRNAs that correlate with certain information regarding cancer. The microRNAs of the invention are selected from the group consisting of hsa-miR-15b, hsa-miR-181b, hsa-miR-191, hsa-miR-200c, and hsa-let-7g. If the expression of these microRNAs is increase, then the increased expression of these microRNAs is diagnostic for cancer, characterizes the cancer, prognosticates an expected response to cancer treatments, and/or prognosticates an expected survival of a patient. Embodiments of this discovery include a method, composition, kit and isolated nucleic acid.
Public/Granted literature
- US20100203513A1 MICRORNA AS BIOMARKER IN CANCER Public/Granted day:2010-08-12
Information query