Invention Grant
US08343911B2 Methods of inhibiting and treating bacterial biofilms by metal chelators
有权
金属螯合剂抑制和治疗细菌生物膜的方法
- Patent Title: Methods of inhibiting and treating bacterial biofilms by metal chelators
- Patent Title (中): 金属螯合剂抑制和治疗细菌生物膜的方法
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Application No.: US12288449Application Date: 2008-10-20
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Publication No.: US08343911B2Publication Date: 2013-01-01
- Inventor: Pradeep K. Singh , Michael J. Welsh , E. Peter Greenberg
- Applicant: Pradeep K. Singh , Michael J. Welsh , E. Peter Greenberg
- Applicant Address: US IA Iowa City
- Assignee: University of Iowa Research Foundation
- Current Assignee: University of Iowa Research Foundation
- Current Assignee Address: US IA Iowa City
- Agency: Nelson Mullins Riley & Scarborough LLP
- Agent Cynthia L. Kanik
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K38/40
Abstract:
The invention presented herein provides methods and compositions for the prevention and treatment of bacterial infections. The methods are based on the discovery that depletion of bioavailable iron stimulates surface motility in bacteria thus inhibiting the ability of a bacterial population to develop into a biofilm.
Public/Granted literature
- US20120142583A1 Methods of inhibiting and treating bacterial biofilms by metal chelators Public/Granted day:2012-06-07
Information query
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