Invention Grant
- Patent Title: Combination of erythropoietin glycoisoforms
- Patent Title (中): 红细胞生成素glycoisoforms的组合
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Application No.: US12093365Application Date: 2006-11-07
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Publication No.: US08343917B2Publication Date: 2013-01-01
- Inventor: Ricardo Agustin Lopez , Marcelo Gustavo Daelli , Dardo Alexis Pereira Bacci , Gabriel Ignacio Amadeo , Miriam Patricia Pereiro , Cristina Noemi Artana , Nestor Maskin , Bernardo Cesar Pistillo , Carolina Didier , Marina Etcheverrigaray , Ricardo Kratje
- Applicant: Ricardo Agustin Lopez , Marcelo Gustavo Daelli , Dardo Alexis Pereira Bacci , Gabriel Ignacio Amadeo , Miriam Patricia Pereiro , Cristina Noemi Artana , Nestor Maskin , Bernardo Cesar Pistillo , Carolina Didier , Marina Etcheverrigaray , Ricardo Kratje
- Applicant Address: AR Santa Fe
- Assignee: Protech Pharma, SA
- Current Assignee: Protech Pharma, SA
- Current Assignee Address: AR Santa Fe
- Agency: RatnerPrestia
- Priority: ARP050104712 20051110
- International Application: PCT/ES2006/070171 WO 20061107
- International Announcement: WO2007/054600 WO 20070518
- Main IPC: A61K38/18
- IPC: A61K38/18 ; A61K9/20 ; A61K9/46 ; C07K14/505 ; C12N5/00 ; C12N15/09
Abstract:
This invention relates to a combination of erythropoietin glycoisoforms, wherein such glycoisoforms may include a quantity of sialic acid ranging from 4 to 10 molecules of sialic acid per molecule of erythropoietin. The combination of glycoisoforms can be used for the treatment or prevention of sepsis, and used to prepare a pharmaceutical composition including such combination. The invention also encompasses a cell line producing a combination of erythropoietin glycoisoforms, procedures to obtain the cell line, a procedure to produce such a combination of glycoisoforms, and methods of treatment and prevention of sepsis.
Public/Granted literature
- US20090220595A1 COMBINATION OF ERYTHROPOIETIN GLYCOISOFORMS Public/Granted day:2009-09-03
Information query
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