Invention Grant
![4-amino-3-(imidazolyl)-pyrazolo[3,4-D]pyrimidines](/docs/US/2013-01-01/US08343975B2/abs.jpg.600x600.jpg)
- Patent Title: 4-amino-3-(imidazolyl)-pyrazolo[3,4-D]pyrimidines
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Application No.: US12557428Application Date: 2009-09-10
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Publication No.: US08343975B2Publication Date: 2013-01-01
- Inventor: Penglie Zhang , Yibin Zeng
- Applicant: Penglie Zhang , Yibin Zeng
- Agency: Kilpatrick, Townsend & Stockton LLP
- Main IPC: A61K31/497
- IPC: A61K31/497 ; C07D487/00
![4-amino-3-(imidazolyl)-pyrazolo[3,4-D]pyrimidines](/abs-image/US/2013/01/01/US08343975B2/abs.jpg.150x150.jpg)
Abstract:
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are 4-amino-3-imidazoyl-pyrazolo[3,4-d]pyrimidine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated disease, and as controls in assays for the identification of competitive CCR1 antagonists.
Public/Granted literature
- US20100069396A1 4-AMINO-3-(IMIDAZOLYL)-PYRAZOLO[3,4-D]PYRIMIDINES Public/Granted day:2010-03-18
Information query
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