Invention Grant
US08343976B2 Compounds, compositions and methods comprising pyrazole derivatives
有权
包含吡唑衍生物的化合物，组合物和方法
- Patent Title: Compounds, compositions and methods comprising pyrazole derivatives
- Patent Title (中): 包含吡唑衍生物的化合物，组合物和方法
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Application No.: US12762899Application Date: 2010-04-19
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Publication No.: US08343976B2Publication Date: 2013-01-01
- Inventor: Stephen David Penrose , Kevin James Doyle
- Applicant: Stephen David Penrose , Kevin James Doyle
- Applicant Address: US CA South San Francisco
- Assignee: Institute for OneWorld Health
- Current Assignee: Institute for OneWorld Health
- Current Assignee Address: US CA South San Francisco
- Agency: Foley & Lardner LLP
- Agent Antoinette F. Konski; Photon Rao
- Main IPC: A61K31/497
- IPC: A61K31/497 ; A61K31/415 ; C07D231/20 ; C07D403/12 ; A61P1/12
Abstract:
The present invention relates to compounds, compositions and methods for treating a disease in an animal, which disease is responsive to inhibiting of functional cystic fibrosis transmembrane conductance regulator (CFTR) polypeptide by administering to a mammal in need thereof an effective amount of a compound defined herein (including those compounds set forth in Tables 1-2 or encompassed by formulas Ia, Ib, IIa, and IIb) or compositions comprising these compounds, thereby treating the disease. The present invention particularly, relates to a method of treating diarrhea and polycystic kidney disease.
Public/Granted literature
- US20100267741A1 Compounds, Compositions and Methods Comprising Pyrazole Derivatives Public/Granted day:2010-10-21
Information query
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