Invention Grant
US08343984B2 Crystalline forms of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide
有权
4-甲基-N- [3-（4-甲基 - 咪唑-1-基）-5-三氟甲基 - 苯基] -3-（4-吡啶-3-基 - 嘧啶-2-基氨基） - 苯甲酰胺的结晶形式
![Crystalline forms of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide](/docs/US/2013-01-01/US08343984B2/abs.jpg.600x600.jpg)
- Patent Title: Crystalline forms of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide
- Patent Title (中): 4-甲基-N- [3-（4-甲基 - 咪唑-1-基）-5-三氟甲基 - 苯基] -3-（4-吡啶-3-基 - 嘧啶-2-基氨基） - 苯甲酰胺的结晶形式
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Application No.: US11995906Application Date: 2006-07-18
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Publication No.: US08343984B2Publication Date: 2013-01-01
- Inventor: Paul W Manley , Wen-Chung Shieh , Paul Allen Sutton , Piotr “Peter” H Karpinski , Raeann Wu , Stéphanie M. Monnier , Jörg Brozio
- Applicant: Paul W Manley , Wen-Chung Shieh , Paul Allen Sutton , Piotr “Peter” H Karpinski , Raeann Wu , Stéphanie M. Monnier , Jörg Brozio
- Applicant Address: CH Basel AT Vienna
- Assignee: Novartis AG,Novartis Pharma GmbH
- Current Assignee: Novartis AG,Novartis Pharma GmbH
- Current Assignee Address: CH Basel AT Vienna
- Agent Stephen Johnson
- International Application: PCT/US2006/027875 WO 20060718
- International Announcement: WO2007/015870 WO 20070208
- Main IPC: A01N43/54
- IPC: A01N43/54 ; A61K31/505 ; C07D239/02
![Crystalline forms of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide](/abs-image/US/2013/01/01/US08343984B2/abs.jpg.150x150.jpg)
Abstract:
Polymorphic forms of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide free base and salts thereof are prepared by various processes.
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