Invention Grant
US08344007B2 Water-soluble polymer-based cantharimides as potentially selective anti-tumor agents
有权
作为潜在选择性的抗肿瘤剂的水溶性聚合物类的陶瓷酰胺
- Patent Title: Water-soluble polymer-based cantharimides as potentially selective anti-tumor agents
- Patent Title (中): 作为潜在选择性的抗肿瘤剂的水溶性聚合物类的陶瓷酰胺
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Application No.: US12428488Application Date: 2009-04-23
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Publication No.: US08344007B2Publication Date: 2013-01-01
- Inventor: Johnny Cheuk-on Tang , Albert Sun-chi Chan , Kim-hung Lam , Chung-hin Chui , Stanton Hon Lung Kok , Marcus Chun Wah Yuen , Sau Hing Chan , Chor Hing Cheng , Filly Cheung
- Applicant: Johnny Cheuk-on Tang , Albert Sun-chi Chan , Kim-hung Lam , Chung-hin Chui , Stanton Hon Lung Kok , Marcus Chun Wah Yuen , Sau Hing Chan , Chor Hing Cheng , Filly Cheung
- Applicant Address: CN Hong Kong
- Assignee: The Hong Kong Polytechnic University
- Current Assignee: The Hong Kong Polytechnic University
- Current Assignee Address: CN Hong Kong
- Agency: Duane Morris LLP
- Agent Siegfried J.W. Ruppert
- Main IPC: A01N43/78
- IPC: A01N43/78 ; A61K31/41
Abstract:
A cantharimide compound may include the backbone of formula (1). R1, R2, R3, and R4 may be independently selected from the group consisting of H, C(O)OR5, C(O)R6, C(O)NR7R8, NR9C(O)R10, N—R11R12, O—R13, S—R14, P(O)(OR15)(OR16), As(O)(OR17)(OR18), SO2R19, SO3R20, and B(OR21). X1 to X4 may be independently selected from the group consisting of nitrogen and carbon, such that X1 to X4 are not all hydrogen. Y1, Y2 and R5 to R21 may be independently selected from the group consisting of hydrogen, C1-12-alkyl, -aryl, heteroaryl, and a bioactive polymer.
Public/Granted literature
- US20100273840A1 WATER-SOLUBLE POLYMER-BASED CANTHARIMIDES AS POTENTIALLY SELECTIVE ANTI-TUMOR AGENTS Public/Granted day:2010-10-28
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