Invention Grant
US08344116B2 Polymers and complexes for delivery of nucleic acids to intracellular targets
有权
用于将核酸递送至细胞内靶标的聚合物和复合物
- Patent Title: Polymers and complexes for delivery of nucleic acids to intracellular targets
- Patent Title (中): 用于将核酸递送至细胞内靶标的聚合物和复合物
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Application No.: US12405313Application Date: 2009-03-17
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Publication No.: US08344116B2Publication Date: 2013-01-01
- Inventor: Young Jik Kwon
- Applicant: Young Jik Kwon
- Applicant Address: US OH Cleveland
- Assignee: Case Western Reserve University
- Current Assignee: Case Western Reserve University
- Current Assignee Address: US OH Cleveland
- Agency: Tarolli, Sundheim, Covell & Tummino LLP
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; C12N15/11 ; A61K48/00
Abstract:
A complex includes a nucleic acid and a cationic polymer with at least one side chain coupled to the nucleic acid. The at least one side chain including an acid degradable amine-bearing ketal or acetal linkage.
Public/Granted literature
- US20090233359A1 POLYMERS AND COMPLEXES FOR DELIVERY OF NUCLEIC ACIDS TO INTRACELLULAR TARGETS Public/Granted day:2009-09-17
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