Invention Grant
US08344139B2 Process for preparing crystalline polymorphic forms of (6R)-L-erythro-tetrahydrobiopterin dihydrochloride
有权
制备（6R）-L-赤型 - 四氢生物喋呤二盐酸盐的结晶多晶形式的方法
- Patent Title: Process for preparing crystalline polymorphic forms of (6R)-L-erythro-tetrahydrobiopterin dihydrochloride
- Patent Title (中): 制备（6R）-L-赤型 - 四氢生物喋呤二盐酸盐的结晶多晶形式的方法
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Application No.: US12776551Application Date: 2010-05-10
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Publication No.: US08344139B2Publication Date: 2013-01-01
- Inventor: Rudolf Moser , Viola Groehn , Thomas Egger , Fritz Blatter
- Applicant: Rudolf Moser , Viola Groehn , Thomas Egger , Fritz Blatter
- Applicant Address: CH Schaffhausen
- Assignee: Merck Eprova AG
- Current Assignee: Merck Eprova AG
- Current Assignee Address: CH Schaffhausen
- Agency: Millen, White, Zelano & Branigan, P.C.
- Main IPC: C07D475/04
- IPC: C07D475/04 ; A61P25/00 ; A61P25/16
Abstract:
Crystal forms of (6R)-L-erythro-tetrahydrobiopterin dihydrochloride, hydrates and solvates and processes for their preparation are provided. These crystal forms are either intermediates for the preparation of stable polymorphic form B or are suitable for solid formulations.
Public/Granted literature
- US20100240667A1 CRYSTALLINE FORMS OF (6R)-L-ERYTHRO-TETRAHYDROBIOPTERIN DIHYDROCHLORIDE Public/Granted day:2010-09-23
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