Invention Grant
- Patent Title: 2-thioethenyl substituted carbapenem derivatives
- Patent Title (中): 2-硫代乙烯基取代的碳青霉烯衍生物
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Application No.: US12656606Application Date: 2010-02-04
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Publication No.: US08344154B2Publication Date: 2013-01-01
- Inventor: Takahisa Maruyama , Yuko Kano , Takashi Ando , Toshiro Sasaki , Kazuhiro Aihara , Toshiki Fujita
- Applicant: Takahisa Maruyama , Yuko Kano , Takashi Ando , Toshiro Sasaki , Kazuhiro Aihara , Toshiki Fujita
- Applicant Address: JP Tokyo-to
- Assignee: Meiji Seika Kaisha, Ltd.
- Current Assignee: Meiji Seika Kaisha, Ltd.
- Current Assignee Address: JP Tokyo-to
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: JP2005-114690 20050412; JP2005-235590 20050816
- Main IPC: C07D277/24
- IPC: C07D277/24 ; C07D277/26
Abstract:
2-Ethenylthio-type carbapenem derivatives of formula (I) or pharmaceutically acceptable salts thereof are provided. The compounds according to the present invention have potent antimicrobial activity and a wide antimicrobial spectrum against pneumococci including penicillin resistant Streptococcus pneumoniae (PRSP), Haemophilus influenzae including β-lactamase-negative, ampicillin-resistant Haemophilus influenzae (BLNAR), and Moraxella (Branhamella) catarrhalis.
Public/Granted literature
- US20100145063A1 2- thioethenyl substituted carbapenem derivatives Public/Granted day:2010-06-10
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