The invention relates to an image sensor, in particular to a CMOS sensor, having a plurality of light sensitive pixels arranged in rows and columns for the generation of output signals proportional to the exposure, wherein column lines are associated with the columns to supply the output signals to at least one column amplifier for amplification, wherein the at least one column amplifier cooperates with the column lines such that the amplification of the respective output signal depends on the capacitance of the respective column line.