The described principles provide a method and system for calibrating an UWB RF positioning system. Means for automated calibration of the UWB RF positioning system allow calibration based on simple user input that does not require accuracy. Thus, the disclosed calibration means enables nomadic deployment of UWB RF positioning systems by enabling fast and easy calibration and re-calibration of the system based on in-use data to correct for changes in the system during use. Furthermore, in an embodiment of the invention, means are provided for direct feedback of calibration accuracy to the user. In a further embodiment of the invention, the full use of a UWB positioning system is enabled by obtaining optimal accuracy even at the outskirts of the tracking space and by providing optimal accuracy for a given number of receivers.