Invention Grant
US08350013B2 Arginine wash in protein purification using affinity chromatography 有权
使用亲和色谱法进行蛋白质纯化中的精氨酸洗涤

  • Patent Title: Arginine wash in protein purification using affinity chromatography
  • Patent Title (中): 使用亲和色谱法进行蛋白质纯化中的精氨酸洗涤
  • Application No.: US11899972
    Application Date: 2007-09-07
  • Publication No.: US08350013B2
    Publication Date: 2013-01-08
  • Inventor: Shujun Sun
  • Applicant: Shujun Sun
  • Applicant Address: US NJ Madison
  • Assignee: Wyeth LLC
  • Current Assignee: Wyeth LLC
  • Current Assignee Address: US NJ Madison
  • Agent Jenny J. Yeh
  • Main IPC: A61K39/395
  • IPC: A61K39/395 C07K1/22
Arginine wash in protein purification using affinity chromatography
Abstract:
The invention relates to methods for isolating a product and/or reducing turbidity and/or impurities from a load fluid comprising the product and one or more impurities by passing the load fluid through a medium, followed by at least one wash solution comprising arginine, and collecting the product using an elution solution. The invention further relates to a product prepared using a method as described herein.
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