A first method for matching skin colors comprises measuring a spectral reflectance curve of an area of skin and determining a blend of pigments to match the skin's color by combining spectral reflectance curves measured for pigments to produce a calculated spectral reflectance curve corresponding to that of the skin. The pigment blend is then used, for example, to pigment a medical prosthesis, so that it matches precisely its wearer's skin. This method avoids the problem of metamerism in which colors that match under a first illumination no longer match under a second illumination. A second method uses a database of pigment blends generated by the first method. The color of an area of skin is measured and a pigment blend is selected from the database that provides a closest match. Apparatus for carrying out such color matching is also provided, together with palettes of suitable pigments for skin color matching.