Invention Grant
US08354110B2 Compositions and methods for the prevention and treatment of autoimmune conditions
有权
用于预防和治疗自身免疫病症的组合物和方法
- Patent Title: Compositions and methods for the prevention and treatment of autoimmune conditions
- Patent Title (中): 用于预防和治疗自身免疫病症的组合物和方法
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Application No.: US12044435Application Date: 2008-03-07
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Publication No.: US08354110B2Publication Date: 2013-01-15
- Inventor: Pedro Santamaria , Anna Moore
- Applicant: Pedro Santamaria , Anna Moore
- Applicant Address: CA Calgary, Alberta US MA Boston
- Assignee: UTI Limited Partnership,The General Hospital Corporation
- Current Assignee: UTI Limited Partnership,The General Hospital Corporation
- Current Assignee Address: CA Calgary, Alberta US MA Boston
- Agency: Foley & Lardner LLP
- Agent Antoinette F. Konski; Laurie Stellman
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/38 ; A01N25/26 ; A01N25/28
Abstract:
The methods include selectively reducing or expanding T cells according to the antigenic specificity of the T cells. Therefore, the present invention can be used to reduce or eliminate pathogenic T cells that recognize autoantigens, such as beta cell specific T cells. As such, the present invention can be used to prevent, treat or ameliorate autoimmune diseases such as IDDM. Furthermore, the present invention can be used to expand desirable T cells, such as anti-pathogenic T cells to prevent, treat and/or ameliorate autoimmune diseases.
Public/Granted literature
- US20090155292A1 COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF AUTOIMMUNE CONDITIONS Public/Granted day:2009-06-18
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