Invention Grant
- Patent Title: Binary deoxyribozyme probes for nucleic acid analysis
- Patent Title (中): 用于核酸分析的二元脱氧核酶探针
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Application No.: US12162605Application Date: 2007-02-04
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Publication No.: US08354227B2Publication Date: 2013-01-15
- Inventor: Dmitry Kolpashchikov
- Applicant: Dmitry Kolpashchikov
- Applicant Address: US NY New York City
- Assignee: Columbia University in the City of New York
- Current Assignee: Columbia University in the City of New York
- Current Assignee Address: US NY New York City
- Agency: Evans & Molinelli PLLC
- Agent Judith A. Evans
- International Application: PCT/US2007/061583 WO 20070204
- International Announcement: WO2008/054834 WO 20080508
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C07H21/00 ; C07H21/02 ; C07H21/04
Abstract:
New binary deoxyribozyme or ribozyme probes and methods are described for nucleic acid analysis, which allows the detection of nucleic acids under mild physiologic conditions with extraordinary specificity and high sensitivity to single nucleotide mismatches without PCR amplification.
Public/Granted literature
- US20100015608A1 BINARY DEOXYRIBOZYME PROBES FOR NUCLEIC ACID ANALYSIS Public/Granted day:2010-01-21
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