Invention Grant
US08354239B2 Fluorescent methods and materials for directed biomarker signal amplification
有权
用于定向生物标记信号放大的荧光方法和材料
- Patent Title: Fluorescent methods and materials for directed biomarker signal amplification
- Patent Title (中): 用于定向生物标记信号放大的荧光方法和材料
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Application No.: US13195736Application Date: 2011-08-01
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Publication No.: US08354239B2Publication Date: 2013-01-15
- Inventor: Brent S. Gaylord , Janice W. Hong , Tsu-Ju Fu , Cheng-Jun Sun , Russell Baldocchi
- Applicant: Brent S. Gaylord , Janice W. Hong , Tsu-Ju Fu , Cheng-Jun Sun , Russell Baldocchi
- Applicant Address: US CA San Diego
- Assignee: Sirigen, Inc.
- Current Assignee: Sirigen, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Wilson, Sonsini, Goodrich & Rosati
- Main IPC: G01N33/53
- IPC: G01N33/53 ; G01N33/533 ; G01N21/76

Abstract:
Methods and compositions are provided that include a multichromophore and/or multichromophore complex for identifying a target biomolecule. A sensor biomolecule, for example, an antibody can be covalently linked to the multichromophore. Additionally, a signaling chromophore can be covalently linked to the multichromophore. The arrangement is such that the signaling chromophore is capable of receiving energy from the multichromophore upon excitation of the multichromophore. Since the sensor biomolecule is capable of interacting with the target biomolecule, the multichromophore and/or multichromophore complex can provide enhanced detection signals for a target biomolecule.
Public/Granted literature
- US20120029155A1 Fluorescent Methods and Materials for Directed Biomarker Signal Amplification Public/Granted day:2012-02-02
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