Invention Grant
- Patent Title: Pyrimidine inhibitors of kinase activity
- Patent Title (中): 嘧啶抑制剂激酶活性
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Application No.: US12788008Application Date: 2010-05-26
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Publication No.: US08354422B2Publication Date: 2013-01-15
- Inventor: Richard F. Clark , Randy L. Bell , Nwe Y. Ba-maung , Scott A. Erickson , Steve D. Fidanze , Robert A. Mantei , George S. Sheppard , Bryan K. Sorensen , Gary T. Wang , Jieyi Wang
- Applicant: Richard F. Clark , Randy L. Bell , Nwe Y. Ba-maung , Scott A. Erickson , Steve D. Fidanze , Robert A. Mantei , George S. Sheppard , Bryan K. Sorensen , Gary T. Wang , Jieyi Wang
- Applicant Address: US IL Abbott Park
- Assignee: Abbott Laboratories Inc.
- Current Assignee: Abbott Laboratories Inc.
- Current Assignee Address: US IL Abbott Park
- Agent Glen J. Gesicki
- Main IPC: C07D403/14
- IPC: C07D403/14 ; C07D413/14 ; A61K31/5377 ; A61K31/506
Abstract:
The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts or solvates thereof, wherein G1, R2, R3, R4, R5, n, p, q, Ar1, and Ar2 are defined in the description. The present invention relates also to methods of making said compounds, and compositions comprising said compounds which are useful for inhibiting kinases such as IGF-1R.
Public/Granted literature
- US20100305126A1 Pyrimidine Inhibitors of Kinase Activity Public/Granted day:2010-12-02
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