Invention Grant
US08354430B2 Monohydrochloride salt of 1-[3-[3-(4-chlorophenyl) propoxy]propyl]-piperidine
有权
1- [3- [3-(4-氯苯基)丙氧基]丙基] - 哌啶的单盐酸盐
- Patent Title: Monohydrochloride salt of 1-[3-[3-(4-chlorophenyl) propoxy]propyl]-piperidine
- Patent Title (中): 1- [3- [3-(4-氯苯基)丙氧基]丙基] - 哌啶的单盐酸盐
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Application No.: US13491229Application Date: 2012-06-07
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Publication No.: US08354430B2Publication Date: 2013-01-15
- Inventor: Manuel Raga , Juan Sallares , Marta Guerrero , Antonio Guglietta , Jean-Michel Arrang , Jean-Charles Schwartz , Holger Stark , Walter Schunack , Xavier Ligneau , Jeanne-Marie Lecomte , Charon Ganellin
- Applicant: Manuel Raga , Juan Sallares , Marta Guerrero , Antonio Guglietta , Jean-Michel Arrang , Jean-Charles Schwartz , Holger Stark , Walter Schunack , Xavier Ligneau , Jeanne-Marie Lecomte , Charon Ganellin
- Applicant Address: FR Paris
- Assignee: Bioprojet
- Current Assignee: Bioprojet
- Current Assignee Address: FR Paris
- Agency: Stites & Harbison, PLLC
- Agent B. Aaron Schulman, Esq.
- Priority: EP05100942 20050210
- Main IPC: A61K31/4453
- IPC: A61K31/4453 ; C07D295/088
![Monohydrochloride salt of 1-[3-[3-(4-chlorophenyl) propoxy]propyl]-piperidine](/abs-image/US/2013/01/15/US08354430B2/abs.jpg.150x150.jpg)
Abstract:
A method is provided for the treatment of sleep apnea and other conditions wherein an effective amount of crystalline 1-[3-[3-(4-chlorophenyl)propoxy]propyl]-piperidine monohydrochloride of formula (I): optionally comprising water up to 6%, and having an X-ray diffractogram that comprises characteristic peaks (2θ) at 11.2°, 19.9°, 20.7° and 34.1°±0.2° is administered to a patient in need thereof.
Public/Granted literature
- US20120289546A1 MONOHYDROCHLORIDE SALT OF 1-[3-[3-(4-CHLOROPHENYL) PROPOXY]PROPYL]-PIPERIDINE Public/Granted day:2012-11-15
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