Invention Grant
US08354526B2 Pyrido [4, 3-D] pyrimidinone derivatives as kinase inhibitors
失效
吡啶并[4,3-D]嘧啶酮衍生物作为激酶抑制剂
![Pyrido [4, 3-D] pyrimidinone derivatives as kinase inhibitors](/docs/US/2013-01-15/US08354526B2/abs.jpg.600x600.jpg)
- Patent Title: Pyrido [4, 3-D] pyrimidinone derivatives as kinase inhibitors
- Patent Title (中): 吡啶并[4,3-D]嘧啶酮衍生物作为激酶抑制剂
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Application No.: US12865367Application Date: 2009-01-27
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Publication No.: US08354526B2Publication Date: 2013-01-15
- Inventor: Qiang Ding , Yahua Liu , Xu Wu , Qihui Jin , Jianwei Che , S. Frank Yan
- Applicant: Qiang Ding , Yahua Liu , Xu Wu , Qihui Jin , Jianwei Che , S. Frank Yan
- Applicant Address: BM Hamilton
- Assignee: IRM LLC
- Current Assignee: IRM LLC
- Current Assignee Address: BM Hamilton
- Agency: Genomics Institute of the Novartis Research Foundation
- Agent Daniel E. Raymond
- International Application: PCT/US2009/032127 WO 20090127
- International Announcement: WO2009/099801 WO 20090813
- Main IPC: C07D345/00
- IPC: C07D345/00
![Pyrido [4, 3-D] pyrimidinone derivatives as kinase inhibitors](/abs-image/US/2013/01/15/US08354526B2/abs.jpg.150x150.jpg)
Abstract:
The invention provides a class of compounds of Formula (I), pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly Syk, ZAP70, KDR, FMS, FLT3, c-Kit, RET, TrkA, TrkB, TrkC, IGR-IR, AIk, c-FMS, or combinations thereof.
Public/Granted literature
- US20110003790A1 PYRIDO [4, 3-D] PYRIMIDINONE DERIVATIVES AS KINASE INHIBITORS Public/Granted day:2011-01-06
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