Invention Grant
- Patent Title: Process for the synthesis of rosuvastatin calcium
- Patent Title (中): 合成罗苏伐他汀钙的方法
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Application No.: US11997070Application Date: 2006-07-26
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Publication No.: US08354530B2Publication Date: 2013-01-15
- Inventor: Marko Zlicar
- Applicant: Marko Zlicar
- Applicant Address: SI Ljubljana
- Assignee: Lek Pharmaceuticals d. d
- Current Assignee: Lek Pharmaceuticals d. d
- Current Assignee Address: SI Ljubljana
- Agency: Luedeka Neely Group, P.C.
- Priority: SI200500220 20050728; SI200500311 20051110
- International Application: PCT/EP2006/007388 WO 20060726
- International Announcement: WO2007/017117 WO 20070215
- Main IPC: C07D239/42
- IPC: C07D239/42

Abstract:
Present invention represents process for the preparation of HMG-CoA reductase inhibitors, in particular rosuvastatin calcium introducing L-malic acid as the source of chirality for the side chain.
Public/Granted literature
- US20080255170A1 Process for the Synthesis of Rosuvastatin Calcium Public/Granted day:2008-10-16
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