A display panel and a manufacture method thereof are provided. The display panel includes a first substrate, a second substrate, and a sealant. The first substrate has a top surface which includes a signal transmission module parallel to an edge of the top surface. The sealant is disposed on the top surface and parallel to the signal transmission module, which is disposed between the top surface and sealant. The sealant is made of a photo-curable material and includes an inner isolation wall, which is exposed via the signal transmission module. The second substrate is disposed on the sealant and includes an inner surface. A light-shielding structure is disposed on the inner surface and close to an edge of the inner surface. The sealant at least partially overlaps the light-shielding structure.