Aspects of a method and system for frequency selection using microstrip transceivers for high-speed applications may include determining an operating frequency for operating one or both of a transmitter and a receiver. A frequency response and/or impedance of one or more transmission lines that may be utilized by the transmitter and/or the receiver may be controlled by adjusting one or more capacitances, communicatively coupled to the transmission lines based on the determined operating frequency. The capacitances may be coupled to the one or more transmission line at arbitrary physical spots, and may comprise capacitors and/or varactors. The capacitors and/or the varactors may be adjusted with a digital signal or an analog signal. The capacitances may comprise a matrix arrangement of capacitors and/or varactors. The one or more transmission lines may comprise a microstrip.