Invention Grant
- Patent Title: Annulus fibrosus detection in intervertebral discs using molecular imaging agents
- Patent Title (中): 使用分子成像剂在椎间盘中检测纤维环
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Application No.: US12370207Application Date: 2009-02-12
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Publication No.: US08357350B2Publication Date: 2013-01-22
- Inventor: Cristina Abucay Tan Hehir , Tiberiu Mircea Siclovan , Kenneth Michael Fish , Nicole Evelyn Barnhardt , John V. Frangioni , Carrie S. Vooght
- Applicant: Cristina Abucay Tan Hehir , Tiberiu Mircea Siclovan , Kenneth Michael Fish , Nicole Evelyn Barnhardt , John V. Frangioni , Carrie S. Vooght
- Applicant Address: US NY Niskayuna
- Assignee: General Electric Company
- Current Assignee: General Electric Company
- Current Assignee Address: US NY Niskayuna
- Agent Eileen B. Gallagher
- Main IPC: A61K51/00
- IPC: A61K51/00 ; A61M36/14
Abstract:
The present invention relates to methods for imaging annulus fibrosus tissue and a quantitative measurement of its local concentration in a sample using an agent comprising the compound of Formula I, a 13C or 2H enriched compound of Formula I, an 19F-labeled derivative of Formula I, a metal-DOTA (1,4,7,10-tetra-azacyclododecane-N,N′,N″,N′″-tetraacetic acid) complex of Formula I, or a radioisotope derivative of Formula I.
Public/Granted literature
- US20100202965A1 ANNULUS FIBROSUS DETECTION IN INTERVERTEBRAL DISCS USING MOLECULAR IMAGING AGENTS Public/Granted day:2010-08-12
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