Invention Grant
US08357368B2 Methods of treating pancreatic or liver cancer using hedgehog antagonists
有权
使用刺猬蛋白拮抗剂治疗胰腺癌或肝癌的方法
- Patent Title: Methods of treating pancreatic or liver cancer using hedgehog antagonists
- Patent Title (中): 使用刺猬蛋白拮抗剂治疗胰腺癌或肝癌的方法
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Application No.: US12756939Application Date: 2010-04-08
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Publication No.: US08357368B2Publication Date: 2013-01-22
- Inventor: Henryk Dudek , Irina Karavanov , Carmen Pepicelli , Karen Kotkow , Lee L. Rubin
- Applicant: Henryk Dudek , Irina Karavanov , Carmen Pepicelli , Karen Kotkow , Lee L. Rubin
- Applicant Address: US MA Lexington
- Assignee: Curis, Inc.
- Current Assignee: Curis, Inc.
- Current Assignee Address: US MA Lexington
- Agency: Ropes & Gray LLP
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K31/44 ; C12Q1/68 ; G01N33/574

Abstract:
The present application is directed to compositions and methods for inhibiting angiogenesis and treating or preventing unwanted cell proliferation, including tumors, by inhibiting the hedgehog pathway, e.g., with an antagonist of the hedgehog pathway such as those disclosed herein.
Public/Granted literature
- US20110008333A1 METHODS OF INHIBITING UNWANTED CELL PROLIFERATION USING HEDGEHOG ANTAGONISTS Public/Granted day:2011-01-13
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