Invention Grant
- Patent Title: Expanding the eukaryotic genetic code
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Application No.: US13443800Application Date: 2012-04-10
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Publication No.: US08357532B2Publication Date: 2013-01-22
- Inventor: Jason W. Chin , T. Ashton Cropp , J. Christopher Anderson , Peter G. Schultz
- Applicant: Jason W. Chin , T. Ashton Cropp , J. Christopher Anderson , Peter G. Schultz
- Applicant Address: US CA La Jolla
- Assignee: The Scripps Research Institute
- Current Assignee: The Scripps Research Institute
- Current Assignee Address: US CA La Jolla
- Agency: Quine Intellectual Property Law Group, P.C
- Main IPC: C12N9/16
- IPC: C12N9/16 ; C12N9/22 ; C07H21/04
Abstract:
This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.
Public/Granted literature
- US20120282689A1 Expanding the Eukaryotic Genetic Code Public/Granted day:2012-11-08
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