Invention Grant
US08357687B2 Macrocyclic indole derivatives useful as hepatitis C virus inhibitors
有权
用作丙型肝炎病毒抑制剂的大环吲哚衍生物
- Patent Title: Macrocyclic indole derivatives useful as hepatitis C virus inhibitors
- Patent Title (中): 用作丙型肝炎病毒抑制剂的大环吲哚衍生物
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Application No.: US13058990Application Date: 2009-08-14
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Publication No.: US08357687B2Publication Date: 2013-01-22
- Inventor: David Craig Mc Gowan , Sandrine Marie Helene Vendeville , Pierre Jean-Marie Bernard Raboisson , Abdellah Tahri
- Applicant: David Craig Mc Gowan , Sandrine Marie Helene Vendeville , Pierre Jean-Marie Bernard Raboisson , Abdellah Tahri
- Applicant Address: IE Little Island, Co. Cork
- Assignee: Tibotec Pharmaceuticals
- Current Assignee: Tibotec Pharmaceuticals
- Current Assignee Address: IE Little Island, Co. Cork
- Agent Andrea Jo Kamage
- Priority: EP08162435 20080814
- International Application: PCT/EP2009/060580 WO 20090814
- International Announcement: WO2010/018233 WO 20100218
- Main IPC: C07D515/08
- IPC: C07D515/08 ; A61K31/407
Abstract:
Inhibitors of HCV replication of formula (I) including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein Y, R1, R2, R4 and n have the meaning defined in the claims. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use in HCV therapy.
Public/Granted literature
- US20110152279A1 MACROCYCLIC INDOLE DERIVATIVES USEFUL AS HEPATITIS C VIRUS INHIBITORS Public/Granted day:2011-06-23
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