Invention Grant
- Patent Title: 2,3-disubstituted piperidine orexin receptor antagonists
- Patent Title (中): 2,3-二取代哌啶食欲素受体拮抗剂
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Application No.: US13125191Application Date: 2009-10-15
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Publication No.: US08357700B2Publication Date: 2013-01-22
- Inventor: Christopher D. Cox , Broc Flores , John D. Schreier
- Applicant: Christopher D. Cox , Broc Flores , John D. Schreier
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent J. Eric Thies; Gerard M. Devlin
- International Application: PCT/US2009/060759 WO 20091015
- International Announcement: WO2010/048016 WO 20100429
- Main IPC: A61K31/04
- IPC: A61K31/04 ; C07D215/38

Abstract:
The present invention is directed to 2,3-disubstituted piperidine amide compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.
Public/Granted literature
- US20110263643A1 2,3-Disubstituted Piperidine Orexin Receptor Antagonists Public/Granted day:2011-10-27
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