Invention Grant
- Patent Title: 2,4-disubstituted pyrrolidine orexin receptor antagonists
- Patent Title (中): 2,4-二取代的吡咯烷食欲肽受体拮抗剂
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Application No.: US13124877Application Date: 2009-10-15
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Publication No.: US08357709B2Publication Date: 2013-01-22
- Inventor: Paul J. Coleman , Christopher D. Cox , John D. Schreier
- Applicant: Paul J. Coleman , Christopher D. Cox , John D. Schreier
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent J. Eric Thies; Gerard M. Devlin
- International Application: PCT/US2009/060754 WO 20091015
- International Announcement: WO2010/048014 WO 20100429
- Main IPC: A61K31/426
- IPC: A61K31/426 ; C07D207/00
Abstract:
The present invention is directed to 2,4-disubstituted pyrrolidine amide compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.
Public/Granted literature
- US20110201652A1 2,4-Disubstituted Pyrrolidine Orexin Receptor Antagonists Public/Granted day:2011-08-18
Information query
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