Invention Grant
- Patent Title: Bicyclic angiotensin II agonists
- Patent Title (中): 双相血管紧张素II激动剂
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Application No.: US11918241Application Date: 2006-04-12
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Publication No.: US08357710B2Publication Date: 2013-01-22
- Inventor: Mathias Alterman , Anders Hallberg , Murugaiah Andappan Murugaiah Subbaiah
- Applicant: Mathias Alterman , Anders Hallberg , Murugaiah Andappan Murugaiah Subbaiah
- Applicant Address: SE Gothenburg
- Assignee: Vicore Pharma AB
- Current Assignee: Vicore Pharma AB
- Current Assignee Address: SE Gothenburg
- Agency: Nixon & Vanderhye
- International Application: PCT/GB2006/001334 WO 20060412
- International Announcement: WO2006/109058 WO 20061019
- Main IPC: A61K31/34
- IPC: A61K31/34 ; A61K31/381 ; A61K31/40 ; A61K31/4174 ; A61K31/42 ; A61K31/425 ; C07D207/33 ; C07D233/20 ; C07D333/14 ; C07D277/22 ; C07D307/38

Abstract:
There is provided a compound of formula I, wherein R1a, R1b, X, Y1, Y2, Y3, Y4, Z1, Z2, R2 and R3 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful as selective agonists of the AT2 receptor, and thus, in particular, in the treatment of inter alia gastrointestinal conditions, such as dyspepsia, IBS and MOF, and cardiovascular disorders.
Public/Granted literature
- US20090069382A1 Bicyclic Angiotensin II Agonists Public/Granted day:2009-03-12
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