Invention Grant
US08357717B2 Spiro group-containing amide compounds having bradykinin 1 receptor (B1R) activity
失效
具有缓激肽1受体（B1R）活性的含螺咯基的酰胺化合物
- Patent Title: Spiro group-containing amide compounds having bradykinin 1 receptor (B1R) activity
- Patent Title (中): 具有缓激肽1受体（B1R）活性的含螺咯基的酰胺化合物
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Application No.: US12700857Application Date: 2010-02-05
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Publication No.: US08357717B2Publication Date: 2013-01-22
- Inventor: Stefan Schunk , Melanie Reich , Michael Engels , Tieno Germann , Ruth Jostock , Sabine Hees
- Applicant: Stefan Schunk , Melanie Reich , Michael Engels , Tieno Germann , Ruth Jostock , Sabine Hees
- Applicant Address: DE Aachen
- Assignee: Gruenenthal GmbH
- Current Assignee: Gruenenthal GmbH
- Current Assignee Address: DE Aachen
- Agency: Crowell & Moring LLP
- Priority: EP09001659 20090206
- Main IPC: A61K31/40
- IPC: A61K31/40 ; A61K31/47
Abstract:
Substituted spiroamide compounds corresponding to formula (I): wherein A, B, Q1, Q2, Q3, Q4, R1, R8, R9a, R9b, R12, R13, R200 and R210 have defined meanings, processes for their preparation, pharmaceutical compositions containing such compounds, and the use of such compounds for treating or inhibiting pain or other conditions mediated at least in part by the bradykinin 1 receptor (B1R).
Public/Granted literature
- US20100234340A1 Substituted Spiroamide Compounds Public/Granted day:2010-09-16
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