Invention Grant
US08357791B2 DNA and proteins or peptides specific of bacteria of the Neisseria meningitidis species, methods for obtaining them and biological applications thereof
有权
脑膜炎奈瑟氏球菌物种细菌特异性的DNA和蛋白质或肽，获得它们的方法及其生物应用
- Patent Title: DNA and proteins or peptides specific of bacteria of the Neisseria meningitidis species, methods for obtaining them and biological applications thereof
- Patent Title (中): 脑膜炎奈瑟氏球菌物种细菌特异性的DNA和蛋白质或肽，获得它们的方法及其生物应用
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Application No.: US13010139Application Date: 2011-01-20
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Publication No.: US08357791B2Publication Date: 2013-01-22
- Inventor: Xavier Nassif , Colin Tinsley
- Applicant: Xavier Nassif , Colin Tinsley
- Applicant Address: FR Paris
- Assignee: Institut National de la Sante et de la Recherche Medicale (INSERM)
- Current Assignee: Institut National de la Sante et de la Recherche Medicale (INSERM)
- Current Assignee Address: FR Paris
- Agency: Nixon & Vanderhye P.C.
- Priority: FR9608768 19960712
- Main IPC: A61K31/7088
- IPC: A61K31/7088
Abstract:
The DNA of the invention are characterized in that they concern the whole or part of genes, with their reading frame, to be found in Neisseria meningitidis, but not in Neisseria gonorrhoeae, or in Neisseria lactamica except the genes involved in the biosynthesis of the polysaccharide capsule, frp A, frp C, opc, por A, rotamase the sequence IC1106, IgA protease, pilline, pilC, transferrin binding proteins and opacity proteins. The invention also concerns the polypeptides corresponding to these DNA and the antibodies directed against these polypeptides. It is applicable in the prevention and the detection of meningococcus induced infections and meningitis.
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