A touch panel scan system is disclosed for detecting a change in mutual capacitance on the surface of a touch panel. A first touch detect device is provided having a transmitter for transmitting a transmit signal to a select one of a plurality of first lines on a first edge of a touch panel to facilitate a single line scan operation. A second touch detect device is interfaced with a select one or ones of second lines on a second edge of the touch panel having a receiver for receiving therefrom and processing thereof transmit signals coupled thereto from the select one or ones of the first lines to detect changes in a mutual capacitance associated with the select one or ones of the second lines and the first line. At least one of the first or second touch detect devices functions as a master and the other functions as a slave, with the master coupled to the slave and generating a SYNC signal to initiate a single scan operation of a select one of the first lines.