A circuit controls a memory arrangement and includes an array of programmable resources and interconnect resources, a reconfiguration port, and a processor. The programmable resources and interconnect resources in the array are initially configured with a reference configuration data-set. The reference configuration data-set configures the programmable resources and interconnect resources to implement a general memory controller. The processor obtains a characteristic of the memory arrangement and selects a particular partial reconfiguration data-set based on the characteristic of the memory arrangement. The processor reconfigures the programmable resources and interconnect resources in the array via the reconfiguration port. The processor reconfigures the programmable resources and interconnect resources with the particular partial reconfiguration data-set. The particular partial reconfiguration data-set partially reconfigures the programmable resources and interconnect resources to implement a portion of a specific memory controller that differs from the general memory controller.