An electrostatically driven high-speed micro droplet switch includes a substrate having an upper surface containing one or more signal electrodes that are selectively connected via a droplet. The switch includes at least one actuation electrode disposed beneath the upper surface of the substrate, the at least one actuation electrode operatively coupled to drive circuitry. The switch includes a frame disposed on or above the upper surface of the substrate that is configured to hold the droplet in substantially the same location during operation of the switch. In one aspect, the frame is configured to absorb variations in the volume of the droplet placed on the switch, leaving the active meniscus not affected by the variation in volume.