Invention Grant
US08367320B2 Apoptosis inducing positive control for expression modulation experiments 有权
细胞凋亡诱导表达调控实验的阳性对照

  • Patent Title: Apoptosis inducing positive control for expression modulation experiments
  • Patent Title (中): 细胞凋亡诱导表达调控实验的阳性对照
  • Application No.: US12810281
    Application Date: 2008-12-29
  • Publication No.: US08367320B2
    Publication Date: 2013-02-05
  • Inventor: Eric Lader
  • Applicant: Eric Lader
  • Applicant Address: US MD Germantown
  • Assignee: Qiagen Sciences, Inc.
  • Current Assignee: Qiagen Sciences, Inc.
  • Current Assignee Address: US MD Germantown
  • Agency: Rankin, Hill & Clark LLP
  • International Application: PCT/IB2008/003644 WO 20081229
  • International Announcement: WO2009/083790 WO 20090709
  • Main IPC: C12Q1/68
  • IPC: C12Q1/68
Apoptosis inducing positive control for expression modulation experiments
Abstract:
The invention pertains to a method for performing an expression modulating analysis or assay, wherein an apoptosis inducing expression modulating compound targeting a repetitive element present in the untranslated region, in particular the 3′ UTRs of protein coding gene transcripts is introduced into cells to induce apoptosis in the cells as a positive control. Also provided are suitable kits and compositions.
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