Invention Grant
- Patent Title: Apoptosis inducing positive control for expression modulation experiments
- Patent Title (中): 细胞凋亡诱导表达调控实验的阳性对照
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Application No.: US12810281Application Date: 2008-12-29
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Publication No.: US08367320B2Publication Date: 2013-02-05
- Inventor: Eric Lader
- Applicant: Eric Lader
- Applicant Address: US MD Germantown
- Assignee: Qiagen Sciences, Inc.
- Current Assignee: Qiagen Sciences, Inc.
- Current Assignee Address: US MD Germantown
- Agency: Rankin, Hill & Clark LLP
- International Application: PCT/IB2008/003644 WO 20081229
- International Announcement: WO2009/083790 WO 20090709
- Main IPC: C12Q1/68
- IPC: C12Q1/68

Abstract:
The invention pertains to a method for performing an expression modulating analysis or assay, wherein an apoptosis inducing expression modulating compound targeting a repetitive element present in the untranslated region, in particular the 3′ UTRs of protein coding gene transcripts is introduced into cells to induce apoptosis in the cells as a positive control. Also provided are suitable kits and compositions.
Public/Granted literature
- US20100285484A1 APOPTOSIS INDUCING POSITIVE CONTROL FOR EXPRESSION MODULATION EXPERIMENTS Public/Granted day:2010-11-11
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