Invention Grant
- Patent Title: Sulfated C-glycoside, method for isolating same and method for synthesizing same
- Patent Title (中): 硫酸化C-糖苷,其分离方法及其合成方法
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Application No.: US13143111Application Date: 2009-12-25
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Publication No.: US08367622B2Publication Date: 2013-02-05
- Inventor: Hitoshi Ishida
- Applicant: Hitoshi Ishida
- Applicant Address: JP Shizuoka
- Assignee: Shizuoka Prefecture Public University Corporation
- Current Assignee: Shizuoka Prefecture Public University Corporation
- Current Assignee Address: JP Shizuoka
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: JP2009-000008 20090103
- International Application: PCT/JP2009/071700 WO 20091225
- International Announcement: WO2010/076879 WO 20100708
- Main IPC: A01N43/04
- IPC: A01N43/04 ; A61K31/70 ; C07H5/02 ; C07H1/00 ; C07H1/06 ; C07H1/08

Abstract:
Provided are a sulfated C-glycoside which is a novel compound serving as a precursor of chafuroside and chafuroside analogs; a method for efficiently producing the sulfated C-glycoside; and a method for efficiently producing chafuroside and chafuroside analogs using said sulfated C-glycoside. A sulfated C-glycoside represented by general formula (A1) or (B1) [wherein R1, R2 and R3 independently represent each a hydrogen atom or an OH group] is obtained by extracting tea leaves or tea tannins with water, a lower alcohol solvent having 1 to 3 carbon atoms or a liquid mixture comprising the same. Alternatively, the sulfated C-glycoside is produced by reacting a flavone C-glycoside such as isovitexin or vitexin with a sulfate group-introducing agent to thereby sulfate the flavone C-glycoside. By heating the sulfated C-glycoside thus obtained, chafuroside and chafuroside analogs are efficiently produced.
Public/Granted literature
- US20120029183A1 SULFATED C-GLYCOSIDE, METHOD FOR ISOLATING SAME AND METHOD FOR SYNTHESIZING SAME Public/Granted day:2012-02-02
Information query
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