Invention Grant
US08367704B2 Process for preparation of 2-methyl-2′ phenylpropionic acid derivatives and novel intermediate compounds
失效
2-甲基-2'苯基丙酸衍生物和新型中间体化合物的制备方法
- Patent Title: Process for preparation of 2-methyl-2′ phenylpropionic acid derivatives and novel intermediate compounds
- Patent Title (中): 2-甲基-2'苯基丙酸衍生物和新型中间体化合物的制备方法
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Application No.: US12865234Application Date: 2009-02-12
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Publication No.: US08367704B2Publication Date: 2013-02-05
- Inventor: Chun-Ho Lee , Ja-Heouk Khoo , Kyoung-Chan Kwon , Hyun Ju
- Applicant: Chun-Ho Lee , Ja-Heouk Khoo , Kyoung-Chan Kwon , Hyun Ju
- Applicant Address: KR Seoul
- Assignee: Yuhan Corporation
- Current Assignee: Yuhan Corporation
- Current Assignee Address: KR Seoul
- Agency: Alston & Bird LLP
- Priority: KR10-2008-0012656 20080212; KR10-2008-0090385 20080912
- International Application: PCT/KR2009/000668 WO 20090212
- International Announcement: WO2009/102155 WO 20090820
- Main IPC: A61K31/445
- IPC: A61K31/445 ; C07D401/04 ; C07D413/14
Abstract:
The present invention relates to a process for preparing 2-methyl-2′-phenylpropionic acid derivatives showing antihistamine activity in more simplified way, intermediate compounds and their preparation processes used therefor. According to the present invention, pharmaceutically useful 2-methyl-2′-phenylpropionic acid derivatives can be prepared with high yield and purity on industrial scale.
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