Invention Grant
- Patent Title: Pharmaceutical compositions
- Patent Title (中): 药物组合物
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Application No.: US12375208Application Date: 2007-07-26
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Publication No.: US08367735B2Publication Date: 2013-02-05
- Inventor: Stanley M. Roberts , Gabriella M. Santoro
- Applicant: Stanley M. Roberts , Gabriella M. Santoro
- Applicant Address: GB Knutsford Cheshire
- Assignee: Crawford Healthcare Holdings Limited
- Current Assignee: Crawford Healthcare Holdings Limited
- Current Assignee Address: GB Knutsford Cheshire
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- Priority: GB0614848.0 20060726
- International Application: PCT/GB2007/050449 WO 20070726
- International Announcement: WO2008/012583 WO 20080131
- Main IPC: A61K31/015
- IPC: A61K31/015 ; A61K31/12 ; C07C49/603

Abstract:
The present invention relates to compounds of formula I or II:—wherein R is an alkyl, alkenyl, alkynyl, aryl, aralkyl, aralkenyl, or aralkynyl group, that may be substituted or unsubstituted, and that optionally includes at least one heteroatom in its carbon skeleton; R1 is hydrogen, or an alkyl, substituted alkyl, alkenyl, alkynyl, aryl, substituted aryl, or aralkyl group; and R2 is an alkyl, alkenyl, alkynyl, aryl, aralkyl, aralkenyl, or aralkynyl group containing 4-12 carbon atoms, that may be substituted or unsubstituted, and that optionally includes at least one heteroatom in its carbon skeleton; provided that in a compound of formula I, when R1 is an iso-propyl or phenyl group, R2 is not an acetyl or tert-butyldimethylsilyl group; and their use in therapeutic, diagnostic and research methods.
Public/Granted literature
- US20090325901A1 IMPROVEMENTS IN PHARMACEUTICAL COMPOSITIONS Public/Granted day:2009-12-31
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