Invention Grant
- Patent Title: TEM8 peptides and vaccines comprising the same
- Patent Title (中): TEM8肽和包含其的疫苗
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Application No.: US12595197Application Date: 2008-04-10
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Publication No.: US08367799B2Publication Date: 2013-02-05
- Inventor: Takuya Tsunoda , Ryuji Osawa
- Applicant: Takuya Tsunoda , Ryuji Osawa
- Applicant Address: JP Kanagawa
- Assignee: OncoTherapy Science, Inc.
- Current Assignee: OncoTherapy Science, Inc.
- Current Assignee Address: JP Kanagawa
- Agency: Kilpatrick Townsend & Stockton LLP
- International Application: PCT/JP2008/000932 WO 20080410
- International Announcement: WO2008/126413 WO 20081023
- Main IPC: C07K5/00
- IPC: C07K5/00

Abstract:
According to the present invention, peptides comprising the amino acid sequence of SEQ ID NO: 3, 4, 9, 23, 25, 30, 60, 63 or 68 were demonstrated to have cytotoxic T lymphocyte (CTL) inducibility. Therefore, the present invention provides a peptide having the amino acid sequence selected from the group of SEQ ID NOs: 3, 4, 9, 23, 25, 30, 60, 63 and 68. The peptide can include one, two, or several amino acid substitutions or addition so long as its CTL inducibility is retained. Furthermore, the present invention provides pharmaceutical agents for treating and/or prophylaxis of tumors, and/or prevention of postoperative recurrence thereof, which comprises any of these peptides. The pharmaceutical agents of this invention include vaccines.
Public/Granted literature
- US20120093843A1 TEM8 PEPTIDES AND VACCINES COMPRISING THE SAME Public/Granted day:2012-04-19
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