Invention Grant
US08367806B2 Protein disulfide isomerase assay method for the in vitro diagnosis of colorectal cancer
有权
蛋白二硫键异构酶测定方法用于体外诊断结肠直肠癌
- Patent Title: Protein disulfide isomerase assay method for the in vitro diagnosis of colorectal cancer
- Patent Title (中): 蛋白二硫键异构酶测定方法用于体外诊断结肠直肠癌
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Application No.: US12999242Application Date: 2009-07-09
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Publication No.: US08367806B2Publication Date: 2013-02-05
- Inventor: Yasemin Ataman-Onal , Corinne Beaulieu , Sandrine Busseret , Jean-Philippe Charrier , Genevieve Choquet-Kastylevsky , Dominique Rolland
- Applicant: Yasemin Ataman-Onal , Corinne Beaulieu , Sandrine Busseret , Jean-Philippe Charrier , Genevieve Choquet-Kastylevsky , Dominique Rolland
- Applicant Address: FR Marcy l'Etoile
- Assignee: Biomerieux
- Current Assignee: Biomerieux
- Current Assignee Address: FR Marcy l'Etoile
- Agency: Oliff & Berridge, PLC
- Priority: FR0854683 20080710
- International Application: PCT/FR2009/051361 WO 20090709
- International Announcement: WO2010/004214 WO 20100114
- Main IPC: C07K16/00
- IPC: C07K16/00 ; A61K39/395 ; A61K35/12
Abstract:
A method for the in vitro diagnosis of colorectal cancer by determining the presence of the protein disulfide isomerase tumor marker in a biological sample taken from a patient suspected of having colorectal cancer using at least one anti-PDI monoclonal antibody directed against a PDI epitope chosen from the epitopes of sequence SEQ ID NO: 1, SEQ ID NO: 2 with an aromatic amino acid having a three-dimensional structure similar to that of PDI, and SEQ ID NO: 3.
Public/Granted literature
- US20110104701A1 PROTEIN DISULFIDE ISOMERASE ASSAY METHOD FOR THE IN VITRO DIAGNOSIS OF COLORECTAL CANCER Public/Granted day:2011-05-05
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