Invention Grant
US08367826B2 6,6-bicyclic ring substituted heterobicyclic protein kinase inhibitors
失效
6,6-双环取代杂双环蛋白激酶抑制剂
- Patent Title: 6,6-bicyclic ring substituted heterobicyclic protein kinase inhibitors
- Patent Title (中): 6,6-双环取代杂双环蛋白激酶抑制剂
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Application No.: US13308694Application Date: 2011-12-01
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Publication No.: US08367826B2Publication Date: 2013-02-05
- Inventor: Radoslaw Laufer , An-Hu Li , Mark J. Mulvihill , Arno G. Steinig
- Applicant: Radoslaw Laufer , An-Hu Li , Mark J. Mulvihill , Arno G. Steinig
- Applicant Address: US NY Farmingdale
- Assignee: OSI Pharmaceuticals, LLC
- Current Assignee: OSI Pharmaceuticals, LLC
- Current Assignee Address: US NY Farmingdale
- Main IPC: C07D471/00
- IPC: C07D471/00

Abstract:
Compounds of the formula and pharmaceutically acceptable salts thereof, wherein X1, X2, X3, X4, X5, X6, X7, R1, and Q1 are defined herein, inhibit the IGF-1R enzyme and are useful for the treatment and/or prevention of hyperproliferative diseases such as cancer, inflammation, psoriasis, allergy/asthma, disease and conditions of the immune system, disease and conditions of the central nervous system.
Public/Granted literature
- US20120077979A1 6,6-Bicyclic Ring Substituted Heterobicyclic Protein Kinase Inhibitors Public/Granted day:2012-03-29
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