To provide a control circuit of power supply unit, power supply unit and control method thereof capable of setting and adjusting a voltage value of output voltage flexibly corresponding to an instruction from outside, a voltage adjusting portion AD for adjusting first voltage setting information inputted from outside to real voltage information is provided and the voltage value of the output voltage of the power supply unit is controlled based on real voltage information outputted from the voltage adjusting portion AD. The first voltage setting information inputted from outside enables a desired output voltage to be set up by adjusting the real voltage information flexibly even if information relating to the setting of voltage set as output voltage to an external device which is a supply destination is different from actually necessary voltage value.