Techniques are provided for selecting channels for a wider bandwidth operation mode of a wireless network, such as wireless network that operates in accordance with the IEEE 802.11n amendment. Alignments of so-called primary and secondary channels are selected to mitigate interference. Interfering sources, such as other transceivers or external interferers, or the energy from their transmissions, are identified and channels are selected. The selected channels are analyzed to determine whether primary-secondary channel assignments for the selected channels are feasible.