A method for interactive defining and managing of a controlled diet, prescribed to a patient by a doctor/dietician, includes the asynchronous execution of at least two different operational cycles. A first operational cycle is effected through an interactive terminal and includes a step, in which the foods to be consumed in a given meal are chosen from a first food data base, quantifying the chosen food and assessing the congruity of the choices with what is prescribed and transmitting the data to a central processing unit. A second operational cycle executed by the doctor/dietician on a central processing unit, includes acquiring the data related to the quantities and to the composition of the foods chosen by this patient and comparing this data with the dietary order, and if possible acquiring updated orders and transmitting the updated orders to the patient's interactive terminal.