Embodiments of a bubble weapon system and methods for inhibiting movement and disrupting operations of vessels are generally described herein. In some embodiments, a bubble weapon is configured to generate a plume of bubbles in water. The plume reduces buoyancy of the water to inhibit movement of a vessel or disrupt operations of the vessel. In some embodiments, the bubble weapon includes a configurable diffuser section that may be configured in a thrust-neutral configuration or a thrust-engaged configuration.