Invention Grant
- Patent Title: Compositions and methods for the treatment of heart failure
- Patent Title (中): 用于治疗心力衰竭的组合物和方法
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Application No.: US12593798Application Date: 2008-04-04
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Publication No.: US08372387B2Publication Date: 2013-02-12
- Inventor: Bruce Edward Markham
- Applicant: Bruce Edward Markham
- Applicant Address: US MI Ann Arbor
- Assignee: Phrixus Pharmaceuticals, Inc.
- Current Assignee: Phrixus Pharmaceuticals, Inc.
- Current Assignee Address: US MI Ann Arbor
- Agency: Honigman Miller Schwartz and Cohn LLP
- Agent Jonathan P. O'Brien; David J. Johnson
- International Application: PCT/US2008/004437 WO 20080404
- International Announcement: WO2008/124088 WO 20081016
- Main IPC: A61K31/74
- IPC: A61K31/74 ; A61K31/765

Abstract:
The invention provides a therapeutic composition comprising an aqueous buffer, and a therapeutic agent that improves the functioning of a diseased heart by decreasing left ventricular end-diastolic pressure and simultaneously increasing left ventricular ejection without affecting the blood pressure or heart rate.
Public/Granted literature
- US20100178269A1 Compositions and Methods for the Treatment of Heart Failure Public/Granted day:2010-07-15
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