A fuel cell system that includes a cell voltage monitoring sub-system that measures the cell voltage of each cell in a fuel cell stack and provides an indication of a low performing or failed cell. The fuel cell system uses the cell voltage monitoring sub-system to determine if one of the wires connected to a bipolar plate in the stack is broken or has otherwise failed. The cell voltage monitoring sub-system uses differential amplifiers to compare the positive side voltage and the negative side voltage of a cell to determine if the cell voltage is low or the cell is failing. By looking at the outputs of two differential amplifiers in the cell voltage monitoring sub-system, it can be determined whether adjacent cells provide an indication of both cells failing, which would indicate that a connection wire has failed.